Spravato has become a critical treatment option for patients with treatment-resistant depression, but its billing structure remains one of the most complex in behavioral health. As we enter 2026, payer expectations are higher, documentation rules are tighter, and coding errors continue to be the leading cause of claim denials in Spravato programs nationwide.

If your clinic is still experiencing inconsistent reimbursement, unexplained underpayments, or recurring denials, the issue is rarely clinical, it’s almost always tied to front-end billing workflows.

This updated 2026 guide breaks down exactly how to bill Spravato the right way, step by step, with the clarity and operational precision your practice needs. And throughout this guide, you’ll see how a dedicated Spravato Billing Services Company like Finnastra can help you streamline your workflows, eliminate denials, and maximize reimbursement.

Why This 2026 Spravato Billing Guide Matters

Spravato claims follow a uniquely strict pathway. From REMS compliance to Prior Authorization to Buy & Bill, every stage requires precision. Yet more than 32% of Spravato claims are denied on the first submission, according to 2025 behavioral health billing benchmarks.

And here’s the real issue:

Most denials are preventable.

Are you confident your team is using the updated 2026 codes?

Are your REMS monitoring notes detailed enough?

Are your PAs perfectly aligned with payer treatment timelines?

If even one answer gives you pause, the revenue risk is real.

Updated 2026 Spravato Billing Codes You Must Use

Accurate CPT and HCPCS coding is the backbone of clean claims. In 2026, payers are enforcing more stringent code-to-documentation alignment.

Essential Spravato Billing Codes (2026 Update)

Medication (Buy & Bill):

  • S0013 – Esketamine, nasal spray, 1 mg

Observation & Monitoring Codes:

  • G2082 – 56 mg dose
  • G2083 – 84 mg dose

Additional coding refinements payer auditors now look for:

  • Induction vs. maintenance phase alignment
  • Correct NDC based on product packaging
  • Time-based observation details for REMS verification
  • Proper documentation of patient tolerance and adverse effects

Even a small mismatch—like the wrong NDC or insufficient monitoring notes, can trigger an audit or a 30–45 day processing delay.

Our Spravato Billing Services are designed to simplify these complexities by ensuring every claim is fully compliant before it ever reaches your payer.

Eligibility & Benefits Verification: The First Line of Defense

Still stuck with claims reduced for “non-covered services”? Eligibility gaps are why.

Spravato benefits vary dramatically by payer, plan type, and patient tier. A single oversight can lead to thousands lost in a single week.

Key components of a proper verification workflow include:

  • Medication coverage validation
  • Cost-sharing details
  • Buy & Bill reimbursement terms
  • SpravatoWithMe savings eligibility
  • Frequency limits for Spravato dosing
  • Exclusions tied to medical necessity

When you work with a dedicated Spravato Billing Services Company like Finnastra, your verification process becomes a structured, multi-step checkpoint that catches issues early.

Prior Authorization for Spravato: 2026 Requirements You Can’t Miss

PA delays remain one of the most costly bottlenecks in Spravato programs.

In 2026, payers added tighter rules around:

  • Documentation of failed antidepressants
  • PHQ-9 and clinical response tracking
  • Visit frequency and treatment duration
  • Clear justification for maintenance phase continuation

More approvals now require escalation-level documentation, not generic progress notes.

Finnastra handles this by creating audit-ready PA packets that include full clinical narratives, updated scoring metrics, and REMS documentation to accelerate approval timelines and reduce risks of denials.

REMS Compliance: The Most Commonly Failed Audit Category

REMS is a non-negotiable. Payers are now cross-referencing:

  • Observation duration
  • Blood pressure logs
  • Pre- and post-administration notes
  • Adverse event monitoring
  • Provider presence and documentation

Any missing detail, no matter how small, can move a claim directly into denial.

As a leading Spravato Billing Services Company, Finnastra ensures all REMS documentation meets 2026 standards, protecting both compliance and reimbursement.

Step-by-Step Workflow: How to Bill Spravato Correctly in 2026

This streamlined process reflects what high-performing Spravato clinics use today:

1. Eligibility & Financial Clearance

Verify coverage, PA requirements, visit limits, and SpravatoWithMe eligibility.

2. Prior Authorization Submission

Submit clinical justification, failed treatments, PHQ-9, REMS confirmation, and treatment plan.

3. Clinical Documentation Collection

Align notes with CPT/HCPCS requirements and induction/maintenance phases.

4. Coding & Claim Preparation

Apply correct codes, NDC, rendering provider, place of service, and observation times.

5. Claim Submission

Submit claims cleanly with all necessary attachments, narratives, and REMS logs.

6. Denial Management & Appeals

Follow payer-specific appeal pathways within 24–48 hours of a denial.

7. AR & Reimbursement Tracking

Reconcile payments, monitor payer trends, and escalate underpayments.

Finastra manages this entire workflow end-to-end, allowing your clinical team to stay fully focused on patient care.

Real Results from Finnastra’s Spravato Billing Model

Across Spravato, Ketamine, and TMS practices, Finnastra consistently delivers:

  • 98% clean claim rate
  • 82% reduction in denials
  • 17–22% increase in reimbursement
  • Near-zero issues during payer audits
  • Faster PA approvals across commercial plans

These results become possible because we eliminate errors before they reach your payer.

Is Your Spravato Program Billing the Right Way?

Ask yourself:

  • Are we using the updated 2026 codes?
  • Do our REMS notes meet audit standards?
  • Are our PAs always approved on the first submission?
  • Are we consistently paid the correct S0013 reimbursement?
  • Do we have a proactive AR workflow to catch payer errors?

If the answer to any question is uncertain, your practice is likely losing revenue unnecessarily.

Finnastra: Your Partner in Accurate, Compliant, High-Performance Spravato Billing

When you work with a dedicated Spravato Billing Services Company like Finnastra, you gain a full RCM team built specifically for Spravato, Ketamine, and TMS programs.

We handle:

  • Coding
  • Eligibility
  • Prior Authorization
  • REMS documentation
  • Buy & Bill optimization
  • AR & appeals
  • Underpayment recovery

All with the goal of stabilizing and maximizing your reimbursement cycle.

Explore how we can support your program here: https://finnastra.com/spravato-billing/

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